Schedule
| Date | Away | Results | Home | Venue |
|---|---|---|---|---|
 Danville | 12 - 7 | Brewer  | James Tucker Stadium | |
| Brewer | 0 - 70 | Priceville  | Bulldog Stadium | |
 Ardmore | 34 - 14 | Brewer | James Tucker Stadium | |
 Russellville | 52 - 0 | Brewer | James Tucker Stadium | |
| Brewer | 7 - 49 | East Limestone  | East Limestone Stadium | |
| Brewer | 13 - 49 | Arab  | Arab High School | |
| Brewer | 28 - 48 | Lee | Milton Frank Stadium | |
 Mae Jemison | 36 - 43 | Brewer | James Tucker Stadium | |
| Brewer | 14 - 55 | Fairview  | Dafford Smith Stadium | |
 Lawrence Co. | 6 - 35 | Brewer | James Tucker Stadium |
Region Standings
2021 5A Region 8
| Pos | Team | W | L | Region W | Region L | PF | OFF PPG | PA | DEF PPG | Streak |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Russellville | 9 | 2 | 6 | 0 | 435 | 39.5 | 182 | 16.5 | W1 |
| 2 |  East Limestone | 5 | 6 | 5 | 1 | 289 | 26.3 | 284 | 25.8 | L3 |
| 3 |  Ardmore | 7 | 4 | 3 | 3 | 246 | 22.4 | 262 | 23.8 | L1 |
| 4 | Lee | 5 | 6 | 3 | 3 | 328 | 29.8 | 330 | 30.0 | L1 |
| 5 |  Brewer | 2 | 8 | 2 | 4 | 161 | 16.1 | 411 | 41.1 | W1 |
| 5 |  Mae Jemison | 2 | 8 | 2 | 4 | 228 | 22.8 | 347 | 34.7 | L2 |
| 7 |  Lawrence Co. | 0 | 10 | 0 | 6 | 117 | 11.7 | 358 | 35.8 | L10 |
