Schedule
| Date | Away | Results | Home | Venue |
|---|---|---|---|---|
 Hartselle | 29 - 0 | Austin  | Austin Stadium | |
| Hartselle | 41 - 0 | Mae Jemison  | Louis Crews Stadium | |
| Hartselle | 35 - 14 | Cullman  | Woodard Stadium | |
 Decatur | 21 - 42 | Hartselle | J.P. Cain Stadium | |
 Columbia | 0 - 1 | Hartselle | J.P. Cain Stadium | |
 Russellville | 21 - 58 | Hartselle | J.P. Cain Stadium | |
 Athens | 34 - 45 | Hartselle | J.P. Cain Stadium | |
| Hartselle | 52 - 35 | Muscle Shoals  | J.F. Moore Stadium | |
 Hazel Green | 7 - 56 | Hartselle | J.P. Cain Stadium | |
 Buckhorn | 20 - 65 | Hartselle | J.P. Cain Stadium | |
 Gardendale | 35 - 28 | Hartselle | J.P. Cain Stadium |
Region Standings
2021 6A Region 8
| Pos | Team | W | L | Region W | Region L | PF | OFF PPG | PA | DEF PPG | Streak |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Hartselle | 10 | 1 | 7 | 0 | 452 | 41.1 | 187 | 17.0 | L1 |
| 2 |  Muscle Shoals | 9 | 2 | 6 | 1 | 418 | 38.0 | 192 | 17.5 | L1 |
| 3 |  Cullman | 7 | 4 | 5 | 2 | 256 | 23.3 | 172 | 15.6 | L2 |
| 4 |  Decatur | 4 | 7 | 4 | 3 | 257 | 23.4 | 261 | 23.7 | L2 |
| 5 |  Athens | 4 | 6 | 3 | 4 | 236 | 23.6 | 309 | 30.9 | L2 |
| 6 |  Buckhorn | 5 | 5 | 2 | 5 | 221 | 22.1 | 254 | 25.4 | L3 |
| 7 |  Hazel Green | 3 | 7 | 1 | 6 | 243 | 24.3 | 310 | 31.0 | L1 |
| 8 |  Columbia | 0 | 10 | 0 | 7 | 30 | 3.0 | 350 | 35.0 | L10 |
All-State Players
| Name | Team | Position | Class |
| Braxton Quattlebaum | 1st | OL | Senior |
| Izayah Fletcher | 2nd | WR | Junior |
| Kaleb "Mookie" Jones | 2nd | LB | Senior |
| JT Blackwood | Honorable Mention | QB | Senior |
| Ri Fletcher | Honorable Mention | RB | Sophomore |
| Crawford Lang | Honorable Mention | PK | Junior |
