Four players scored in double digits for Brewer but it was not enough as Cullman outscored the Patriots 13-10 to pick up the victory.
Hope West led Brewer with 16 points while Jacie Andrews added 12 points and Leisha Steiger and Chloe Danylo both had 11 points.
Anna Katherine Eastman led Cullman with 19 points. She knocked down a jumper with no time on the clock to force overtime. Alexandria Barker added 15 points.
Brewer (0-1) overcame a 6-point deficit in the fourth quarter to take a two-point lead with only seconds remaining before the Cullman (1-0) shot at the buzzer.
